SRI-30827 | DAT modualtor | Probechem Biochemicals

Chemical Structure : SRI-30827

SRI-30827 (SRI 30827)

Catalog No.: PC-22426Not For Human Use, Lab Use Only.

SRI-30827 is a selective, allosteric modulator of dopamine transporter (DAT), inhibits DA uptake in rat synaptosomes with IC50 of 0.5 nM, counteracts Tat-induced potentiation of cocaine reward.

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Biological Activity

SRI-30827 is a selective, allosteric modulator of dopamine transporter (DAT), inhibits DA uptake in rat synaptosomes with IC50 of 0.5 nM, counteracts Tat-induced potentiation of cocaine reward.

Physicochemical Properties

M.Wt	455.57
Formula	C30H25N5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2,2-diphenylethyl)-2-(7-methylimidazo[1,2-a]pyridin-6-yl)quinazolin-4-amine

References

1. Sun WL, et al. Sci Rep. 2017 Jun 16;7(1):3694.

2. Hammond HR, et al. NeuroImmune Pharm Ther. 2024 Mar 25;3(1):1-6.

3. Rothman RB, et al. J Pharmacol Exp Ther. 2015;353:529–538.

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SRI-30827 (SRI 30827)

Biological Activity

Physicochemical Properties

References

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