SRI-31277 | TGF-β inhibitor | Probechem Biochemicals

Chemical Structure : SRI-31277

SRI-31277 (SRI 31277)

Catalog No.: PC-21884Not For Human Use, Lab Use Only.

SRI-31277 is a tripeptide inhibitor of thrombospondin 1 activation of TGF-β, specifically inhibits TGF-β activation mediated through TSP-1 with pIC50 of 8.28 nM.

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Biological Activity

SRI-31277 is a tripeptide inhibitor of thrombospondin 1 activation of TGF-β, specifically inhibits TGF-β activation mediated through TSP-1 with pIC50 of 8.28 nM.

Physicochemical Properties

M.Wt	387.48
Formula	C17H33N5O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-((S)-2-acetamido-3-hydroxypropanamido)-6-amino-N-((S)-1-amino-4-methyl-1-oxopentan-2-yl)hexanamide

References

1. Lu A, et al. Am. J. Pathol. 2016, 186, 678–690.

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SRI-31277 (SRI 31277)

Biological Activity

Physicochemical Properties

References

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