SRI-35241 | TGF-β inhibitor | Probechem Biochemicals

Chemical Structure : SRI-35241

SRI-35241 (SRI 35241 )

Catalog No.: PC-21885Not For Human Use, Lab Use Only.

SRI-35241 is a potent inhibitor of thrombospondin 1 activation of TGF-β, specifically inhibits TGF-β activation mediated through TSP-1 with pIC50 of 8.12 nM, 79% inhibition at 100 nM.

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Biological Activity

SRI-35241 is a potent inhibitor of thrombospondin 1 activation of TGF-β, specifically inhibits TGF-β activation mediated through TSP-1 with pIC50 of 8.12 nM, 79% inhibition at 100 nM.

Physicochemical Properties

M.Wt	258.32
Formula	C11H22N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-acetamido-5-amino-N-(1-amino-2-methyl-1-oxopropan-2-yl)pentanamide

References

1. Mark J Suto, et al. ACS Med Chem Lett. 2020 May 7;11(6):1130-1136.

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SRI-35241 (SRI 35241 )

Biological Activity

Physicochemical Properties

References

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