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Chemical Structure : ST-193
CAS No.: 489416-12-8
Catalog No.: PC-42388Not For Human Use, Lab Use Only.
ST-193 (ST193) is a potent, selective, broad-spectrum arenavirus entry inhibitor with IC50 of 1.6 nM against LASV pseudotypes, targets arenavirus envelope glycoprotein.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $188 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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ST-193 (ST193) is a potent, selective, broad-spectrum arenavirus entry inhibitor with IC50 of 1.6 nM against LASV pseudotypes, targets arenavirus envelope glycoprotein.
ST-193 also inhibits pseudotypes generated with other arenavirus envelopes with IC50 of 0.2-12 nM, but exhibited no antiviral activity against pseudotypes incorporating either the GP from the LASV-related arenavirus LCMV or the unrelated G protein from vesicular stomatitis virus (IC50>10 uM).
ST-193 exhibits antiviral activity against Lassa virus (LASV) in a guinea pig model (i.p.).
| M.Wt | 371.4748 | |
| Formula | C24H25N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 150 mg/mL |
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| Chemical Name/SMILES |
1H-Benzimidazol-5-amine, 1-(4-methoxyphenyl)-N-[[4-(1-methylethyl)phenyl]methyl]- |
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1. Larson RA, et al. J Virol. 2008 Nov;82(21):10768-75.
2. York J, et al. J Virol. 2008 Nov;82(21):10932-9.
3. Cashman KA, et al. Antiviral Res. 2011 Apr;90(1):70-9.
4. Dai D, et al. Bioorg Med Chem Lett. 2013 Feb 1;23(3):744-9.
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