Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : ST-193
Catalog No.: PC-42388Not For Human Use, Lab Use Only.
ST-193 (ST193) is a potent, selective, broad-spectrum arenavirus entry inhibitor with IC50 of 1.6 nM against LASV pseudotypes, targets arenavirus envelope glycoprotein.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
ST-193 (ST193) is a potent, selective, broad-spectrum arenavirus entry inhibitor with IC50 of 1.6 nM against LASV pseudotypes, targets arenavirus envelope glycoprotein; Also inhibits pseudotypes generated with other arenavirus envelopes with IC50 of 0.2-12 nM, but exhibited no antiviral activity against pseudotypes incorporating either the GP from the LASV-related arenavirus LCMV or the unrelated G protein from vesicular stomatitis virus (IC50>10 uM); exhibits antiviral activity against Lassa virus (LASV) in a guinea pig model (i.p.).
| M.Wt | 371.4748 | |
| Formula | C24H25N3O | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
DMSO: ≥ 150 mg/mL |
|
1. Larson RA, et al. J Virol. 2008 Nov;82(21):10768-75.
2. York J, et al. J Virol. 2008 Nov;82(21):10932-9.
3. Cashman KA, et al. Antiviral Res. 2011 Apr;90(1):70-9.
4. Dai D, et al. Bioorg Med Chem Lett. 2013 Feb 1;23(3):744-9.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
