Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-GPCR-5-HT Receptor-ST1936 oxalate
ST1936 oxalate

Chemical Structure : ST1936 oxalate

CAS No.: 1782228-83-4

Add to Favorites

ST1936 oxalate (ST 1936)

Catalog No.: PC-73301Not For Human Use, Lab Use Only.

ST1936 is a potent, selective 5-HT6 receptor agonist with Ki of 13 nM, >10-fold selectivity over 5-HT7 and 5-HT2B receptors.

Packing Price Stock Quantity
25 mg Get quote
100 mg Get quote
500 mg Get quote
1 g Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ST1936 is a potent, selective 5-HT6 receptor agonist with Ki of 13 nM, >10-fold selectivity over 5-HT7 and 5-HT2B receptors.
ST1936 displays moderate affinity for human α2 adrenergic receptors (Ki = 300 nM).
ST1936 was shown to increase Ca2+ concentration and phosphorylation of Fyn kinase, and regulate the activation of ERK1/2 in cloned cells.
ST1936 reduced the frequency of spontaneous excitatory postsynaptic currents with IC50 of 1.3 uM, inhibited corticostriatal glutamatergic transmission.

Physicochemical Properties

M.Wt 326.777
Formula C15H19ClN2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

References

1. Riccioni T, et al. Eur J Pharmacol. 2011 Jul 1;661(1-3):8-14.

2. Borsini F, et al. J Psychopharmacol. 2015 Jul;29(7):802-11.

3. Tassone A, et al. Neuropharmacology. 2011 Sep;61(4):632-7.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: