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Chemical Structure : ST1936 oxalate
Catalog No.: PC-73301Not For Human Use, Lab Use Only.
ST1936 is a potent, selective 5-HT6 receptor agonist with Ki of 13 nM, >10-fold selectivity over 5-HT7 and 5-HT2B receptors.
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ST1936 is a potent, selective 5-HT6 receptor agonist with Ki of 13 nM, >10-fold selectivity over 5-HT7 and 5-HT2B receptors.
ST1936 displays moderate affinity for human α2 adrenergic receptors (Ki = 300 nM).
ST1936 was shown to increase Ca2+ concentration and phosphorylation of Fyn kinase, and regulate the activation of ERK1/2 in cloned cells.
ST1936 reduced the frequency of spontaneous excitatory postsynaptic currents with IC50 of 1.3 uM, inhibited corticostriatal glutamatergic transmission.
| M.Wt | 326.777 | |
| Formula | C15H19ClN2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Riccioni T, et al. Eur J Pharmacol. 2011 Jul 1;661(1-3):8-14.
2. Borsini F, et al. J Psychopharmacol. 2015 Jul;29(7):802-11.
3. Tassone A, et al. Neuropharmacology. 2011 Sep;61(4):632-7.
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