STAT3 inhibitor NA16

Chemical Structure : STAT3 inhibitor NA16

Catalog No.: PC-24045Not For Human Use, Lab Use Only.

STAT3 inhibitor NA16 is a nifuroxazide analog and STAT3 inhibitor, downregulates FoxP3 expression with IC50 of 4.7 uM in TCR-stimulated total T cells.

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Biological Activity

STAT3 inhibitor NA16 is a nifuroxazide analog and STAT3 inhibitor, downregulates FoxP3 expression with IC50 of 4.7 uM in TCR-stimulated total T cells.

Physicochemical Properties

M.Wt	317.26
Formula	C14H11N3O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-N'-((5-nitrofuran-2-yl)methylene)-2,3-dihydrobenzo[b][1,4]dioxine-6-carbohydrazide

References

1. García-Díaz N, et al. Eur J Immunol. 2025 Feb;55(2):e202451225.

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