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STAT5b inhibitor 7

Chemical Structure : STAT5b inhibitor 7

CAS No.: 1818390-58-7

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STAT5b inhibitor 7 (Capstafin prodrug)

Catalog No.: PC-61628Not For Human Use, Lab Use Only.

STAT5b inhibitor 7 (Capstafin prodrug) is the pivaloyloxymethyl ester prodrug of Capstafin, which is a potent, selective STAT5b inhibitor with Ki of 0.34 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    STAT5b inhibitor 7 (Capstafin prodrug) is the pivaloyloxymethyl ester prodrug of Capstafin, which is a potent, selective STAT5b inhibitor with Ki of 0.34 uM.
    STAT5b inhibitor 7 inhibits STAT5b with selectivity over STAT5a in human tumor cells, inhibits cell viability and induces apoptosis in human tumor cells in a STAT5-dependent manner.

    Physicochemical Properties

    M.Wt 909.941
    Formula C41H69NO17P2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    ((((4-((8-methylnonanamido)methyl)-1,2-phenylene)bis(oxy))bis(oxo-l5-phosphanetriyl))tetrakis(oxy))tetrakis(methylene) tetrakis(2,2-dimethylpropanoate)

    References

    1. Elumalai N, et al. ACS Chem Biol. 2015 Dec 18;10(12):2884-90.

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