STD-101-D1 |CAS:2151041-09-5 Probechem Biochemicals

Chemical Structure : STD-101-D1

STD-101-D1

Catalog No.: PC-61776Not For Human Use, Lab Use Only.

STD-101-D1 is a novel brain permeable, G protein-biased beta-1 adrenergic receptor (ADRB1) partial agonist with EC50 of 16.9 nM.

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Biological Activity

STD-101-D1 is a novel brain permeable, G protein-biased beta-1 adrenergic receptor (ADRB1) partial agonist with EC50 of 16.9 nM.
STD-101-D1 engages very little beta-arrestin recruitment compared to the unbiased agonist isoproterenol.
STD-101-D1 also inhibits the acute peripheral and CNS TNFα response induced by LPS both in vitro and in vivo.

Physicochemical Properties

M.Wt	333.384
Formula	C18H23NO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-4-(2-hydroxy-3-((2-(2-methoxyphenoxy)ethyl)amino)propoxy)phenol

References

1. Yi B, et al. PLoS One. 2017 Jul 26;12(7):e0180319.

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STD-101-D1

Biological Activity

Physicochemical Properties

References

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