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STF-31

Chemical Structure : STF-31

CAS No.: 724741-75-7

STF-31 (STF31)

Catalog No.: PC-45543Not For Human Use, Lab Use Only.

A selective GLUT1 inhibitor that does not bind to other glucose transporters.

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10 mg $88 In stock
25 mg $148 In stock
50 mg $238 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

STF-31 is a selective GLUT1 inhibitor with IC50 of 1 uM, does not bind to other glucose transporters.
STF-31 selectively kills RCCs by specifically targeting glucose uptake through GLUT1 and exploiting the unique dependence of these cells on GLUT1 for survival.
STF-31 also inhibits the enzymatic activity of NAMPT in a biochemical assay in vitro.

Physicochemical Properties

M.Wt 423.5279
Formula C23H25N3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 34 mg/mL

Chemical Name/SMILES

Benzamide, 4-[[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinyl-

References

1. Chan DA, et al. Sci Transl Med. 2011 Aug 3;3(94):94ra70.

2. Adams DJ, et al. ACS Chem Biol. 2014 Oct 17;9(10):2247-54.

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