Chemical Structure : STF-62247
CAS No.: 315702-99-9
Catalog No.: PC-42248Not For Human Use, Lab Use Only.
STF-62247 is a small molecule Autophagy inducer that induces autophagy and selectively induces lethality in VHL-deficient RCC cells.
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| 25 mg | $118 | In stock | |
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STF-62247 is a small molecule Autophagy inducer that induces autophagy and selectively induces lethality in VHL-deficient RCC cells.
STF-62247 induces cytotoxicity and reduces tumor growth in VHL-deficient cells in a HIF-independent manner, PI3K and Golgi trafficking are required as initial signals in STF-62247-induced autophagy.
| M.Wt | 267.3488 | |
| Formula | C15H13N3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 31 mg/mL |
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| Chemical Name/SMILES |
2-Thiazolamine, N-(3-methylphenyl)-4-(4-pyridinyl)- |
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1. Turcotte S, et al. Cancer Cell. 2008 Jul 8;14(1):90-102.
2. Turcotte S, et al. Autophagy. 2008 Oct;4(7):944-6.
3. Chan DA, et al. Cell Cycle. 2008 Oct;7(19):2987-90.
4. Kozako T, et al. Oncotarget. 2018 Jun 12;9(45):27645-27655.

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