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STING activator Compound 11

Chemical Structure : STING activator Compound 11

CAS No.: 2259341-80-3

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STING activator Compound 11

Catalog No.: PC-73369Not For Human Use, Lab Use Only.

STING activator Compound 11 is a potent, small molecule activator/agonist of human STING with EC50 of 66 nM (HEK, R232).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    STING activator Compound 11 is a potent, small molecule activator/agonist of human STING with EC50 of 66 nM (HEK, R232).
    Compound 11 showed significantly enhanced potency compared with G10.

    Physicochemical Properties

    M.Wt 492.464
    Formula C24H17F5N2O2S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    4-(3,5-difluorobenzyl)-2-methyl-3-oxo-N-(2,4,6-trifluorobenzyl)-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide

    References

    1. Monali Banerjee, et al. PLoS One. 2020 Sep 10;15(9):e0237743.

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