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Chemical Structure : STING agonist C11
Catalog No.: PC-61228Not For Human Use, Lab Use Only.
STING agonist C11 is a novel cell-permeable STING agonist that activates IFN-dependent signaling processes and induces IFN secretion from human cells.
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STING agonist C11 is a novel cell-permeable STING agonist that activates IFN-dependent signaling processes and induces IFN secretion from human cells.
STING agonist C11 induces transcription and translation of interferon-dependent antiviral genes, induces canonical IRF3 phosphorylation and ISG transcription in a manner that requires STING but not MAVS or TRIF.
STING agonist C11 potently blocks replication of multiple emerging Alphavirus types including Chikungunya, Ross River, Mayaro, and O'nyong'nyong viruses.
| M.Wt | 382.438 | |
| Formula | C19H18N4O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Gall B, et al. J Virol. 2017 Dec 20. pii: JVI.01913-17.
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