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Chemical Structure : STING inhibitor C-176
CAS No.: 314054-00-7
Catalog No.: PC-35311Not For Human Use, Lab Use Only.
STING inhibitor C-176 (C176) is a covalent, in vivo-active, small-molecule inhibitor of STING, attenuates STING-associated autoinflammatory disease in mice.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $118 | In stock | |
| 25 mg | $178 | In stock | |
| 50 mg | $258 | In stock | |
| 100 mg | Get quote |
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STING inhibitor C-176 (C176) is a covalent, in vivo-active, small-molecule inhibitor of STING, attenuates STING-associated autoinflammatory disease in mice.
C176 markedly reduces the CMA-mediated induction of serum levels of type I IFNs and IL-6 in vivo.
C176 directly targets mouse STING (mmSTING) but not human STING (hsSTING).
| M.Wt | 358.091 | |
| Formula | C11H7IN2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-(4-iodophenyl)-5-nitrofuran-2-carboxamide |
|
1. Haag SM, et al. Nature. 2018 Jul 4. doi: 10.1038/s41586-018-0287-8.
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