STING inhibitor C-178 | STING inhibitor| Probechem Biochemicals

Chemical Structure : STING inhibitor C-178

CAS No.: 329198-87-0

STING inhibitor C-178 (STING inhibitor C178)

Catalog No.: PC-35310Not For Human Use, Lab Use Only.

STING inhibitor C-178 is a covalent, small-molecule inhibitor of STING, blocks palmitoylation (PMA)-induced clustering of STING.

Packing	Price	Stock
5 mg	$88	In stock
10 mg	$128	In stock
25 mg	$218	In stock
50 mg	$358	In stock
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Biological Activity

STING inhibitor C-178 (C178) is a covalent, small-molecule inhibitor of STING, blocks palmitoylation (PMA)-induced clustering of STING.
C-178 covalently binds to Cys91, directly targets mouse STING (mmSTING) but not human STING (hsSTING).

Physicochemical Properties

M.Wt	322.276
Formula	C17H10N2O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(dibenzo[b,d]furan-3-yl)-5-nitrofuran-2-carboxamide

References

1. Haag SM, et al. Nature. 2018 Jul 4. doi: 10.1038/s41586-018-0287-8.

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STING inhibitor C-178 (STING inhibitor C178)

Biological Activity

Physicochemical Properties

References

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