Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Immunology/Inflammation-STING-STING inhibitor THIQi
STING inhibitor THIQi

Chemical Structure : STING inhibitor THIQi

CAS No.: 2377105-91-2

Add to Favorites

STING inhibitor THIQi

Catalog No.: PC-24980Not For Human Use, Lab Use Only.

STING inhibitor THIQi is a potent, orthosteric STING inhibitor with IC50 of 84 nM in HAQ STING cGAMP displacement assays, inhibits cGAMP-induced IFNβ in PBMCs with IC50 of 29 nM.

Packing Price Stock Quantity
50 mg Get quote
100 mg Get quote
250 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

STING inhibitor THIQi is a potent, orthosteric STING inhibitor with IC50 of 84 nM in HAQ STING cGAMP displacement assays, inhibits cGAMP-induced IFNβ in PBMCs with IC50 of 29 nM.

Physicochemical Properties

M.Wt 491.97
Formula C28H26ClNO5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(3S,4S)-2-(4-(tert-butyl)-3-chlorophenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid

References

1. Tony Siu, et al. ACS Med Chem Lett. 2018 Dec 6;10(1):92-97.

2. Xie T, et al. Nat Commun. 2025 Jul 1;16(1):5695.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: