Catalog No.: PC-61251Not For Human Use, Lab Use Only.
STX3451 is a non-steroidal sulphamate analogue of 2-methoxyoestradiol (2ME2) and microtubule disruptor, shows anti-proliferative activity against NCI 60 cell lines with mean GI50 of 50 nM.
STX3451 is a non-steroidal sulphamate analogue of 2-methoxyoestradiol (2ME2) and microtubule disruptor, shows anti-proliferative activity against NCI 60 cell lines with mean GI50 of 50 nM.
STX3451 induces apoptosis in human malignant peripheral nerve sheath tumour (MPNST) cell lines.
STX3451 inhibits both PI3 kinase and mTOR signalling pathways, selectively kills MPNST-derived cells, but also halts growth of other tumour-derived NF1 cell lines.
