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Chemical Structure : SU0383
Catalog No.: PC-72025Not For Human Use, Lab Use Only.
SU0383 (SU 0383) is a potent, dual inhibitor of repair enzyme OGG1 and NUDT1 (MTH1) with IC50 of 34 nM and 490 nM, respectively.
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SU0383 (SU 0383) is a potent, dual inhibitor of repair enzyme OGG1 and NUDT1 (MTH1) with IC50 of 34 nM and 490 nM, respectively.
SU0383 displayed low toxicity in two human cell lines at 10 uM, SU0383 increases sensitivity of tumor cells to oxidative stress.
| M.Wt | 626.732 | |
| Formula | C33H34N6O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO (6.3 mg/mL) |
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1. Tahara YK, et al. ACS Chem Biol. 2019 Dec 20;14(12):2606-2615.
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