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Chemical Structure : SU 16f
Catalog No.: PC-62329Not For Human Use, Lab Use Only.
SU 16f is a potent and selective PDGFRβ inhibitor with IC50 of 10 nM, displays >14-fold, >229-fold and >10,000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively.
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SU 16f is a potent and selective PDGFRβ inhibitor with IC50 of 10 nM, displays >14-fold, >229-fold and >10,000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively; inhibits proliferation of HUVEC and NIH3T3 cells in vitro (IC50 =0.11 uM).
| M.Wt | 386.451 | |
| Formula | C24H22N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Cao N, et al. Science. 2016 Jun 3;352(6290):1216-20.
2. Andersen RK, et al. Stem Cell Res Ther. 2015 Oct 8;6:196.
3. Lee E, et al. Sci Rep. 2014 Jul 28;4:5853.
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