Catalog No.: PC-27751Not For Human Use, Lab Use Only.
Halicin (SU3327) is a potent, selective and substrate competitive c-Jun N-terminal kinase (JNK) inhibitor with IC50 of 0.7 uM, inhibits TNF-α stimulated phosphorylation of c-Jun with IC50 of 6.23 uM in HeLa cells.
Halicin (SU3327) is a potent, selective and substrate competitive c-Jun N-terminal kinase (JNK) inhibitor with IC50 of 0.7 uM, inhibits TNF-α stimulated phosphorylation of c-Jun with IC50 of 6.23 uM in HeLa cells.
Halicin (SU3327) shows an IC50 of 239 nM in displacing pepJIP1, as measured by a DELFIA assay.
Halicin (SU3327) is 142 fold less active against p38α, and completely inactive against Akt kinase, metalloprotease LF (lethal factor) and the proprotein convertase furin.
Halicin (SU3327) improves cardiac function and reduces heart damage during IR.
