SW-044248 |CAS:522650-83-5 Probechem Biochemicals

Chemical Structure : SW-044248

CAS No.: 522650-83-5

SW-044248 (SW 044248;SW044248)

Catalog No.: PC-45667Not For Human Use, Lab Use Only.

SW-044248 is a potent, selective inhibitor of Topoisomerase I (Topo I), inhibits Top I differently from camptothecin, shows selective toxicity for some NSCLC cell lines.

Packing	Price	Stock
5 mg	$88	In stock
10 mg	$128	In stock
25 mg	$218	In stock
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Biological Activity

SW-044248 is a potent, selective inhibitor of Topoisomerase I (Topo I), inhibits Top I differently from camptothecin, shows selective toxicity for some NSCLC cell lines.

Physicochemical Properties

M.Wt	421.5153
Formula	C22H23N5O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 30 mg/mL
Chemical Name/SMILES	Butanamide, 2-[(5-ethyl-5H-1,2,4-triazino[5,6-b]indol-3-yl)thio]-N-(2-methoxyphenyl)-

References

1. Zubovych IO, et al. Mol Cancer Ther. 2016 Jan;15(1):23-36.

2. Kim HS, et al. Cell. 2013 Oct 24;155(3):552-66.

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SW-044248 (SW 044248;SW044248)

Biological Activity

Physicochemical Properties

References

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