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SW203668

Chemical Structure : SW203668

CAS No.: 1673556-40-5

SW203668 (SW 203668)

Catalog No.: PC-20380Not For Human Use, Lab Use Only.

SW203668 (SW 203668) is a potent, tumor-specific, irreversible stearoyl CoA desaturase (SCD) inhibitor with high sensitity to H2122 cell (IC50=22 nM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    SW203668 (SW 203668) is a potent, tumor-specific, irreversible stearoyl CoA desaturase (SCD) inhibitor with high sensitity to H2122 cell (IC50=58 nM).
    SW203668 shows selective and potent cytotoxicity against cancer cell lines expressing cytochrome P450 4F11.

    Physicochemical Properties

    M.Wt 389.47
    Formula C22H19N3O2S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-(amino(phenyl)methyl)-N-(6-methoxybenzo[d]thiazol-2-yl)benzamide

    References

    1. JM, et al. Nat Chem Biol. 2016 Apr;12(4):218-25.

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