SW203668 | SCD inhibitor | Probechem Biochemicals

Chemical Structure : SW203668

SW203668 (SW 203668)

Catalog No.: PC-20380Not For Human Use, Lab Use Only.

SW203668 (SW 203668) is a potent, tumor-specific, irreversible stearoyl CoA desaturase (SCD) inhibitor with high sensitity to H2122 cell (IC50=22 nM).

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Biological Activity

SW203668 (SW 203668) is a potent, tumor-specific, irreversible stearoyl CoA desaturase (SCD) inhibitor with high sensitity to H2122 cell (IC50=58 nM).
SW203668 shows selective and potent cytotoxicity against cancer cell lines expressing cytochrome P450 4F11.

Physicochemical Properties

M.Wt	389.47
Formula	C22H19N3O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(amino(phenyl)methyl)-N-(6-methoxybenzo[d]thiazol-2-yl)benzamide

References

1. JM, et al. Nat Chem Biol. 2016 Apr;12(4):218-25.

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SW203668 (SW 203668)

Biological Activity

Physicochemical Properties

References

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