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SW IV-52

Chemical Structure : SW IV-52

CAS No.: 845745-37-1

SW IV-52 ((S)-SW IV-52 hydrochloride)

Catalog No.: PC-72362Not For Human Use, Lab Use Only.

SW IV-52 is a pro-apoptotic small molecule SMAC mimetic and XIAP-inhibitor.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    SW IV-52 is a pro-apoptotic small molecule SMAC mimetic and XIAP inhibitor.

    Physicochemical Properties

    M.Wt 479.06
    Formula C25H39ClN4O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-[3,3-Dimethyl-2(S)-(2(S)-methylamino-propionylamino)-butyryl]-pyrrolidine-2(S)-carboxylic acid (1,2,3,4-tetrahydro-naphthalen-1(R)-yl)-amide Hydrochloride

    References

    1. Garg G, et al. Mol Cancer. 2014 Mar 7;13:50.

    2. Hashim YM, et al. Mol Oncol. 2014 Jul;8(5):956-67.

    3. Hashim YM, et al. J Exp Clin Cancer Res. 2017 Jan 17;36(1):14.

    4. Oost TK, et al. J Med Chem. 2004;47:4417–4426.

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