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Chemical Structure : SY-LB-35
Catalog No.: PC-49109Not For Human Use, Lab Use Only.
SY-LB-35 is a highly effective small molecule full agonist of bone morphogenetic protein (BMP) receptor signaling, significantly increases the cell number and cell viability in the C2C12 myoblast cell line.
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SY-LB-35 is a highly effective small molecule full agonist of bone morphogenetic protein (BMP) receptor signaling, significantly increases the cell number and cell viability in the C2C12 myoblast cell line.
SY-LB-35 (0.01-10 uM) stimulated canonical Smad and non-canonical PI3K/Akt, ERK, p38 and JNK intracellular signaling pathways, similar to BMP2-stimulated responses.
SY-LB-35 strongly stimulate Smad phosphorylation and nuclear translocation, induce robust increases in PI3K/Akt signaling.
SY-LB-35 is a full agonists of BMP receptor signaling.
| M.Wt | 249.273 | |
| Formula | C15H11N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Sheyda Najafi, et al. Sci Rep. 2022 Jul 15;12(1):12146.
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