SYM2081 | GluK2 agonist | Probechem Biochemicals

Chemical Structure : SYM2081

CAS No.: 31137-74-3

SYM2081 (SYM-2081)

Catalog No.: PC-23690Not For Human Use, Lab Use Only.

SYM2081 is a potent, specific agonist of glutamate receptor ionotropic kainate 2 (GluK2) with EC50 of 0.2 uM, inhibits inhibits [3H]-kainate binding with IC50 of 35 nM.

Packing	Price	Stock
5 mg	$138	In stock
10 mg	$218	In stock
25 mg	$388	In stock
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Biological Activity

SYM2081 is a potent, specific agonist of glutamate receptor ionotropic kainate 2 (GluK2) with EC50 of 0.2 uM, inhibits inhibits [3H]-kainate binding with IC50 of 35 nM.

Physicochemical Properties

M.Wt	161.16
Formula	C6H11NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,4R)-2-Amino-4-methylpentanedioic acid

References

1. Carver JM, et al. Brain Res. 1996 May 13;720(1-2):69-74.

2. Zhang YR, et al. Sci Transl Med. 2024 Dec 11;16(777):eadq9133.

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SYM2081 (SYM-2081)

Biological Activity

Physicochemical Properties

References

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