Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Membrane Transporter/Ion Channel-iGluR-SYM2206
SYM2206

Chemical Structure : SYM2206

CAS No.: 173952-44-8

Add to Favorites

SYM2206 (SYM-2206)

Catalog No.: PC-45528Not For Human Use, Lab Use Only.

SYM2206 is an allosteric, non-competitive antagonist of the AMPA receptor with IC50 of 2.8 uM.

Packing Price Stock Quantity
10 mg $128 In stock
25 mg $218 In stock
50 mg $368 In stock
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SYM2206 is an allosteric, non-competitive antagonist of the AMPA receptor with IC50 of 2.8 uM.
SYM2206 acts allosterically at the same regulatory site as GYKI 52466 and 53655 and other benzodiazepines but does not bind to the central diazepine binding site.
SYM2206 shows selectivity for AMPA relative to kainate receptor sub-types.

Physicochemical Properties

M.Wt 366.4137
Formula C20H22N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1,3-Dioxolo[4,5-g]phthalazine-6(5H)-carboxamide, 8-(4-aminophenyl)-5-methyl-N-propyl-

References

1. Pei XF, et al. Bioorg Med Chem Lett. 1999 Feb 22;9(4):539-42.

2. Li P, et al. Nature. 1999 Jan 14;397(6715):161-4.

3. Behr J, et al. Eur J Neurosci. 2002 Sep;16(5):861-7.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: