Catalog No.: PC-63211Not For Human Use, Lab Use Only.
Sabutoclax (BI-97C1) is a potent, pan Bcl-2 family proteins inhibitor that inhibits the binding of BH3 peptides to Bcl-XL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31, 0.32, 0.20 and 0.62 uM.
Sabutoclax (BI-97C1) is a potent, pan Bcl-2 family proteins inhibitor that inhibits the binding of BH3 peptides to Bcl-XL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31, 0.32, 0.20 and 0.62 uM.
Sabutoclax (BI-97C1) potently inhibits cell growth of human prostate cancer, lung cancer, and lymphoma cell lines withEC50 of 0.13, 0.56, and 0.049 uM, respectively.
Sabutoclax (BI-97C1) displays superior single-agent antitumor efficacy in prostate cancer mouse xenograft model.
