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Sacituzumab

Chemical Structure : Sacituzumab

CAS No.:

Sacituzumab (Anti-human TACSTD2 mAb, human IgG1-Kappa)

Catalog No.: PC-Ab1045Not For Human Use, Lab Use Only.

Sacituzumab is a human Trop-2 mAB that targets the Trop-2 protein and attaches to it. Sacituzumab govitecan is an antibody–drug conjugate composed of an antibody targeting the human trophoblast cell-surface antigen 2 (Trop-2), which is expressed in the majority of breast cancers, coupled to SN-38 (topoisomerase I inhibitor) through a proprietary hydrolyzable linker..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Sacituzumab is a human Trop-2 mAB that targets the Trop-2 protein and attaches to it. Sacituzumab govitecan is an antibody–drug conjugate composed of an antibody targeting the human trophoblast cell-surface antigen 2 (Trop-2), which is expressed in the majority of breast cancers, coupled to SN-38 (topoisomerase I inhibitor) through a proprietary hydrolyzable linker.

Physicochemical Properties

M.Wt
Formula Human IgG1-Kappa
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

References

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