Sacubitril | Neprilysin inhibitor | Probechem Biochemicals

Chemical Structure : Sacubitril

CAS No.: 149709-62-6

Catalog No.: PC-28475Not For Human Use, Lab Use Only.

Sacubitril (AHU-377) is a potent and orally active neprilysin (NEP) inhibitor with IC50 of 5 nM, a component of the Sacubitril/Valsartan (LCZ696).

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10 mg	$58	In stock
25 mg	$88	In stock
50 mg	$128	In stock
100 mg	$198	In stock
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Biological Activity

Sacubitril (AHU-377) is a potent and orally active neprilysin (NEP) inhibitor with IC50 of 5 nM, a component of the Sacubitril/Valsartan (LCZ696).

M.Wt	411.50
Formula	C24H29NO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(((2S,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid

1. Gu J, et al. J Clin Pharmacol. 2010 Apr;50(4):401-14.