Chemical Structure : Safingol
Catalog No.: PC-23349Not For Human Use, Lab Use Only.
Safingol (L-threo-dihydrosphingosine) is a putative inhibitor of sphingosine kinase (SphK) and PKCalpha (PKCα), suppresses growth of human oral squamous cell carcinoma (SCC) cells, significantly inhibits PKC isoforms.
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Safingol (L-threo-dihydrosphingosine) is a putative inhibitor of sphingosine kinase (SphK) and PKCalpha (PKCα), suppresses growth of human oral squamous cell carcinoma (SCC) cells, significantly inhibits PKC isoforms.
M.Wt | 301.52 | |
Formula | C18H39NO2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Tsukamoto S, et al. Mol Cancer Ther. 2015 Oct;14(10):2303-12.
2. Dickson MA, et al. Clin Cancer Res. 2011 Apr 15;17(8):2484-92.
3. Coward J, et al. Autophagy. 2009 Feb;5(2):184-93.
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