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SalA-VS-08

Chemical Structure : SalA-VS-08

CAS No.: 2439152-14-2

SalA-VS-08

Catalog No.: PC-22909Not For Human Use, Lab Use Only.

SalA-VS-08 is a potent, highly selective kappa-opioid receptor (KOR) agonist with Ki of 68.5 nM and EC50 of 854 nM, shows G protein-biased KOR agonist activity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SalA-VS-08 is a potent, highly selective kappa-opioid receptor (KOR) agonist with Ki of 68.5 nM and EC50 of 854 nM, shows G protein-biased KOR agonist activity.

Physicochemical Properties

M.Wt 396.47
Formula C22H25FN4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4'-(cyclopropylmethyl)-1-(3-fluorobenzoyl)-2'-methyl-4'H-spiro[piperidine-4,7'-pyrazolo[1,5-a]pyrimidin]-5'(6'H)-one

References

1. Kristina Puls, et al. J Med Chem. 2024 Aug 1. doi: 10.1021/acs.jmedchem.4c00590.

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