Chemical Structure : Sapacitabine
Catalog No.: PC-61331Not For Human Use, Lab Use Only.
An orally available, nucleoside analog prodrug of CNDAC that interferes with DNA synthesis by causing single-strand DNA breaks.
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An orally available, nucleoside analog prodrug of CNDAC that interferes with DNA synthesis by causing single-strand DNA breaks; induces arrest of the cell division cycle at G2 phase, demonstrates potent anti-tumor activity in both blood and solid tumors.
Chemotherapeutic Agents
Phase 3 Clinical
M.Wt | 490.64 | |
Formula | C26H42N4O5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Hanaoka K, et al. Int J Cancer. 1999 Jul 19;82(2):226-36.
2. Wu M, et al. Cancer Res. 2003 May 15;63(10):2477-82.
3. Katz MH, et al. Cancer Res. 2003 Sep 1;63(17):5521-5.
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