Chemical Structure : Sapacitabine
CAS No.: 151823-14-2
Catalog No.: PC-61331Not For Human Use, Lab Use Only.
Sapacitabine (CYC-682) is an orally available, nucleoside analog prodrug of CNDAC that interferes with DNA synthesis by causing single-strand DNA breaks.
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Sapacitabine (CYC-682) is an orally available, nucleoside analog prodrug of CNDAC that interferes with DNA synthesis by causing single-strand DNA breaks.
Sapacitabine induces arrest of the cell division cycle at G2 phase, demonstrates potent anti-tumor activity in both blood and solid tumors.
| M.Wt | 490.64 | |
| Formula | C26H42N4O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-[1-(2-Cyano-2-deoxy-β-D-arabinofuranosyl)-1,2-dihydro-2-oxo-4-pyrimidinyl]hexadecanamide |
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1. Hanaoka K, et al. Int J Cancer. 1999 Jul 19;82(2):226-36.
2. Wu M, et al. Cancer Res. 2003 May 15;63(10):2477-82.
3. Katz MH, et al. Cancer Res. 2003 Sep 1;63(17):5521-5.

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