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Chemical Structure : Saquinavir
CAS No.: 127779-20-8
Catalog No.: PC-45133Not For Human Use, Lab Use Only.
Saquinavir (Ro 31-8959) is a potent and selective inhibitor of HIV-1 protease with IC50 of 0.5-6 nM in cell assays.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $178 | In stock | |
| 25 mg | $288 | In stock | |
| 50 mg | $428 | In stock | |
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| 200 mg | Get quote | ||
| 1 g | Get quote |
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Saquinavir (Ro 31-8959) is a potent and selective inhibitor of HIV-1 protease with IC50 of 0.5-6 nM in cell assays.
Saquinavir (Ro 31-8959) binds to the active site of the viral protease and prevents cleavage of viral polyproteins, preventing maturation of the virus; inhibits both HIV-1 and HIV-2 proteases.
Saquinavir (Ro 31-8959) is used to treat or prevent HIV/AIDS.
| M.Wt | 670.8408 | |
| Formula | C38H50N6O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Butanediamide, N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, (2S)- |
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1. Martin JA, et al. Biochem Biophys Res Commun. 1991 Apr 15;176(1):180-8.
2. Craig JC, et al. Antiviral Res. 1991 Dec;16(4):295-305.
3. Kräusslich HG. J Virol. 1992 Jan;66(1):567-72.
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