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Chemical Structure : Saredutant
Catalog No.: PC-70189Not For Human Use, Lab Use Only.
Saredutant (SR48968) is a potent and selective non-peptide antagonist of the neurokinin A (NK2) receptor.
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Saredutant (SR48968) is a potent and selective non-peptide antagonist of the neurokinin A (NK2) receptor.
Saredutant (SR48968) displays >1,000-fold selectivity over NK3 receptor, and does not affect the effects of bradykinin, angiotensin or bombesin.
Saredutant (SR48968) inhibits the bronchoconstriction induced by neurokinin A in guinea pigs>
Saredutant (SR48968) inhibits the cholinergic response of the isolated guinea-pig main bronchus to electrical field stimulation.
| M.Wt | 552.5345 | |
| Formula | C31H35Cl2N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Emonds-Alt X, et al. Life Sci. 1992;50(15):PL101-6.
2. Martin CA, et al. Eur J Pharmacol. 1993 Oct 26;243(3):309-12.
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