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Scutellarin

Chemical Structure : Scutellarin

CAS No.: 27740-01-8

Scutellarin

Catalog No.: PC-23197Not For Human Use, Lab Use Only.

Scutellarin is an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, also shows anti-HIV-1 activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Scutellarin is an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, also shows anti-HIV-1 activity.

Physicochemical Properties

M.Wt 462.36
Formula C21H18O12
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

References

1. Ke Y, et al. Biochem Biophys Res Commun. 2016 Dec 18.

2. Zhao S, et al. Int Immunopharmacol. 2016 Nov;40:458-465

3. Zhang GH, et al. Biochem Biophys Res Commun. 2005 Sep 2;334(3):812-6.

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