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Chemical Structure : SelDeg51
Catalog No.: PC-21336Not For Human Use, Lab Use Only.
SelDeg51 (Selective Degrader of FKBP51) is a potent, selective FKBP51 PROTAC with Kd of 18 nM, Emax=90%.
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SelDeg51 (Selective Degrader of FKBP51) is a potent, selective FKBP51 PROTAC with Kd of 18 nM, Emax=90%.
SelDeg51 increases the Dexamethasone-induced expression of the endogenous GR target genes GILZand FKBP5, reflecting the removal of FKBP51-mediated repression of GR signalling.
| M.Wt | 1343.62 | |
| Formula | C72H91FN8O14S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Thomas M Geiger, et al. Angew Chem Int Ed Engl. 2023 Nov 9:e202309706.
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