Chemical Structure : Senktide
CAS No.: 106128-89-6
Catalog No.: PC-63134Not For Human Use, Lab Use Only.
Senktide is a potent, selective agonist of neuromedin K3 (NK3) receptor (EC50 =0.5-3 nM), less potently agonizes the NK1 receptor (EC50=35 µM) and is without effect on the NK2 receptor.
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Senktide is a potent, selective agonist of neuromedin K3 (NK3) receptor (EC50 =0.5-3 nM), less potently agonizes the NK1 receptor (EC50=35 µM) and is without effect on the NK2 receptor.
| M.Wt | 841.978 | |
| Formula | C40H55N7O11S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
DFFGLM (Modifications: Asp-1 = Succinyl-Asp, Phe-3 = Me-Phe, Met-6 = C-terminal amide) |
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1. Byk G, et al. J Med Chem. 1996 Aug 2;39(16):3174-8.
2. Sarau HM, et al. J Pharmacol Exp Ther. 1997 Jun;281(3):1303-11.
3. Harrison T, et al. Bioorg Med Chem Lett. 1998 Jun 2;8(11):1343-8.

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