Chemical Structure : Seralutinib
CAS No.: 1619931-27-9
Catalog No.: PC-47008Not For Human Use, Lab Use Only.
Seralutinib (GB002) is a potent, selective kinase inhibitor that targets PDGFRα/β, CSF1R, and c-KIT, and increases BMPR2, shows potential for treatment of pulmonary arterial hypertension.
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Seralutinib (GB002) is a potent, selective kinase inhibitor that targets PDGFRα/β, CSF1R, and c-KIT, and increases BMPR2, shows potential for treatment of pulmonary arterial hypertension.
M.Wt | 469.545 | |
Formula | C27H27N5O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-[3-[(1S)-1-[[6-(3,4-dimethoxyphenyl)pyrazin-2-yl]amino]ethyl]phenyl]-5-methylpyridine-3-carboxamide |
1. Frantz RP, et al. Pulm Circ. 2021 Nov 11;11(4):20458940211057071.
2. Galkin A, et al. Eur Respir J. 2022 Jun 9:2102356.
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