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Seralutinib

Chemical Structure : Seralutinib

CAS No.: 1619931-27-9

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Seralutinib (GB002, PK-10571)

Catalog No.: PC-47008Not For Human Use, Lab Use Only.

Seralutinib (GB002) is a potent, selective kinase inhibitor that targets PDGFRα/β, CSF1R, and c-KIT, and increases BMPR2, shows potential for treatment of pulmonary arterial hypertension.

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5 mg $98 In stock
10 mg $148 In stock
25 mg $258 In stock
50 mg $428 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Seralutinib (GB002) is a potent, selective kinase inhibitor that targets PDGFRα/β, CSF1R, and c-KIT, and increases BMPR2, shows potential for treatment of pulmonary arterial hypertension.

Physicochemical Properties

M.Wt 469.545
Formula C27H27N5O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-[3-[(1S)-1-[[6-(3,4-dimethoxyphenyl)pyrazin-2-yl]amino]ethyl]phenyl]-5-methylpyridine-3-carboxamide

References

1. Frantz RP, et al. Pulm Circ. 2021 Nov 11;11(4):20458940211057071.

2. Galkin A, et al. Eur Respir J. 2022 Jun 9:2102356.

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