Sergliflozin etabonate (GW869682X)

Chemical Structure : Sergliflozin etabonate

Catalog No.: PC-20194Not For Human Use, Lab Use Only.

Sergliflozin etabonate (GW869682X) is a potent, selective SGLT2 inhibitor with IC50 of 7.5 nM (hSGLT2), >200-fold selectivity over hSGLT1.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Sergliflozin etabonate (GW869682X) is a potent, selective SGLT2 inhibitor with IC50 of 7.5 nM (hSGLT2), >200-fold selectivity over hSGLT1.

M.Wt	448.46
Formula	C23H28O9
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl (((2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(2-(4-methoxybenzyl)phenoxy)tetrahydro-2H-pyran-2-yl)methyl) carbonate

1. Katsuno K, et al. J Pharmacol Exp Ther. 2007 Jan;320(1):323-30.

2. Pajor AM, et al. J Pharmacol Exp Ther. 2008 Mar;324(3):985-91.

3. Fujimori Y, et al. Eur J Pharmacol. 2009 May 1;609(1-3):148-54.