Serlopitant | NK1R antagonist | Probechem Biochemicals

Chemical Structure : Serlopitant

Catalog No.: PC-63390Not For Human Use, Lab Use Only.

Serlopitant (VPD-737, MK-0594) is a potent, selective substance P/neurokinin 1 (NK1) receptor for treating chronic pruritus.

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Biological Activity

Serlopitant (VPD-737, MK-0594) is a potent, selective substance P/neurokinin 1 (NK1) receptor for treating chronic pruritus.

M.Wt	555.537
Formula	C29H28F7NO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((3aR,4R,5S,7aS)-5-((1R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-4-(4 fluorophenyl)octahydro-2H-isoindol-2-yl)cyclopent-2-en-1-one

1. Yosipovitch G, et al. J Am Acad Dermatol. 2018 May;78(5):882-891.e10.