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Simpinicline

Chemical Structure : Simpinicline

CAS No.: 753015-44-0

Simpinicline (OC-02)

Catalog No.: PC-38681Not For Human Use, Lab Use Only.

Simpinicline (OC-02) is a highly selective nicotinic acetylcholine receptor (nAChR) agonist, exhibits potent antiviral activity against the SARS-CoV-2 variants in cell culture with IC50 of 40 nM.

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    Biological Activity

    Simpinicline (OC-02) is a highly selective nicotinic acetylcholine receptor (nAChR) agonist, exhibits potent antiviral activity against the SARS-CoV-2 variants in cell culture with IC50 of 40 nM.

    Physicochemical Properties

    M.Wt 175.235
    Formula C10H13N3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    5-{(1E)-2-[(3R)-pyrrolidin-3-yl]ethen-1-yl}pyrimidine

    References

    1. Alexandris, N. et al. Toxicology reports, 8, 73-83.

    2. Sungnak, W.,et al. Nature medicine, 26(5), 681-687.

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