Chemical Structure : Siponimod
CAS No.:
1230487-00-9
Siponimod
(BAF-312, BAF312)
Catalog No. : PC-43000Not For Human Use, Lab Use Only.
Siponimod (BAF312) is a potent, selective S1P1/S1P5 receptor modulator with EC50 of 0.39/0.0.98 nM, >1,000-fold selectivity over S1P2/3/4.
Packing Price Stock Quantity 5 mg $58 In stock 0 1 2 3 4 5 10 mg $88 In stock 0 1 2 3 4 5 25 mg $128 In stock 0 1 2 3 4 5 50 mg $198 In stock 0 1 2 3 4 5 100 mg $328 In stock 0 1 2 3 4 5 250 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4300001
Biological Activity
Siponimod (BAF312) is a potent, selective S1P1/S1P5 receptor modulator with EC50 of 0.39/0.0.98 nM, >1,000-fold selectivity over S1P2/3/4.
Physicochemical Properties
M.Wt
516.595
Formula
C29H35F3N2O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 30 mg/mL
Chemical Name/SMILES
3-Azetidinecarboxylic acid, 1-[[4-[(1E)-1-[[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]imino]ethyl]-2-ethylphenyl]methyl]-
References
1. Pan S, et al. ACS Med Chem Lett.
2. Gergely P, et al. Br J Pharmacol.
3. Fryer RM, et al. PLoS One.
4. Selmaj K, et al. Lancet Neurol.
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