Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Cell Cycle/DNA Damage-Wee1-Sirusertib
Sirusertib

Chemical Structure : Sirusertib

CAS No.: 3066062-53-8

Add to Favorites

Sirusertib (ACR-2316, ACR2316)

Catalog No.: PC-27502Not For Human Use, Lab Use Only.

Sirusertib (ACR-2316) is a potent, selective dual WEE1/PKMYT1 (Myt1) inhibitor, shows potent WEE1 inhibition and robust activation of CDK1, CDK2, and PLK1, to induce potent tumor cell death.

Packing Price Stock Quantity
50 mg Get quote
100 mg Get quote
250 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Sirusertib (ACR-2316) is a potent, selective dual WEE1/PKMYT1 (Myt1) inhibitor, shows potent WEE1 inhibition and robust activation of CDK1, CDK2, and PLK1, to induce potent tumor cell death.

    Physicochemical Properties

    M.Wt 511.59
    Formula C27H29N9O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-allyl-6-((1-methyl-1H-indazol-5-yl)amino)-1-(6-((1-methylpiperidin-4-yl)oxy)pyridin-2-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one

    References

    1. Portia Lombardo, et al. Mol Cancer Ther (2025) 24 (10_Supplement): C112.

    2. Patent WO2024254490 A1 2024-12-12.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: