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Sob-AM2

Chemical Structure : Sob-AM2

CAS No.: 2128258-47-7

Sob-AM2

Catalog No.: PC-25536Not For Human Use, Lab Use Only.

Sob-AM2 is the CNS-selective prodrug of thyroid hormone analog sobetirome (Thyromimetic GC-1, QRX-431)), which is a potent T3 mimic that binds to the TH receptors with subtype selectivity for thyroid hormone receptor beta (TRβ) over thyroid hormone receptor alpha (TRα).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Sob-AM2 is the CNS-selective prodrug of thyroid hormone analog sobetirome (Thyromimetic GC-1, QRX-431)), which is a potent T3 mimic that binds to the TH receptors with subtype selectivity for thyroid hormone receptor beta (TRβ) over thyroid hormone receptor alpha (TRα).

Physicochemical Properties

M.Wt 341.45
Formula C21H27NO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(4-(4-Hydroxy-3-isopropylbenzyl)-3,5-dimethylphenoxy)-N-methylacetamide

References

1. Bárez-López S, et al. Thyroid. 2018 Sep;28(9):1211-1220.

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