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Solifenacin

Chemical Structure : Solifenacin

CAS No.: 242478-37-1

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Solifenacin (YM905 free base)

Catalog No.: PC-28476Not For Human Use, Lab Use Only.

Solifenacin (YM905 free base) is a potent, M3-preferential muscarinic receptor (mAChR) antagonist with pKi values of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively.

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100 mg $58 In stock
250 mg $88 In stock
1 g $148 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Solifenacin (YM905 free base) is a potent, M3-preferential muscarinic receptor (mAChR) antagonist with pKi values of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively.

Physicochemical Properties

M.Wt 362.47
Formula C23H26N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-(R)-Quinuclidin-3-yl 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

References

1. Uchida T, et al. Br J Clin Pharmacol. 2004 Jul;58(1):4-7.

2. Kobayashi S, et al. Life Sci. 2004 Jan 2;74(7):843-53.

3. Ikeda K, et al. Naunyn Schmiedebergs Arch Pharmacol. 2002 Aug;366(2):97-103.

4. Kobayashi S, et al. Jpn J Pharmacol. 2001 Jul;86(3):281-8.

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