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Solifenacin succinate

Chemical Structure : Solifenacin succinate

CAS No.: 242478-38-2

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Solifenacin succinate (YM905)

Catalog No.: PC-28477Not For Human Use, Lab Use Only.

Solifenacin succinate (YM905) is a potent, M3-preferential muscarinic receptor (mAChR) antagonist with pKi values of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively.

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100 mg $48 In stock
250 mg $78 In stock
1 g $128 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Solifenacin succinate (YM905) is a potent, M3-preferential muscarinic receptor (mAChR) antagonist with pKi values of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively.

Physicochemical Properties

M.Wt 480.56
Formula C27H32N2O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-(R)-Quinuclidin-3-yl 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate succinate

References

1. Uchida T, et al. Br J Clin Pharmacol. 2004 Jul;58(1):4-7.

2. Kobayashi S, et al. Life Sci. 2004 Jan 2;74(7):843-53.

3. Ikeda K, et al. Naunyn Schmiedebergs Arch Pharmacol. 2002 Aug;366(2):97-103.

4. Kobayashi S, et al. Jpn J Pharmacol. 2001 Jul;86(3):281-8.

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