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Chemical Structure : Solithromycin
CAS No.: 760981-83-7
Catalog No.: PC-45378Not For Human Use, Lab Use Only.
A novel fluoroketolide with lower MICs than those of telithromycin and macrolides.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $232 | In stock | |
| 50 mg | $720 | In stock |
Bulk size, bulk discount!
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A novel fluoroketolide with lower MICs than those of telithromycin and macrolides; binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis; exhibits MICs of 7.5, 40, and 125 ng/ml for Streptococcus pneumoniae,Staphylococcus aureus, and Haemophilus influenzae, respectively.
Bacterial Infection
Approved
| M.Wt | 845.0088 | |
| Formula | C43H65FN6O10 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 32 mg/mL |
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| Chemical Name/SMILES |
2H-Oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone, 1-[4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl]-4-ethyl-7-fluorooctahydro-11-methoxy-3a,7,9,11,13,15-hexamethyl-10-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (3aS, |
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1. Waites KB, et al. Antimicrob Agents Chemother. 2009 May;53(5):2139-41.
2. Lemaire S, et al. Antimicrob Agents Chemother. 2009 Sep;53(9):3734-43.
3. Roblin PM, et al. Antimicrob Agents Chemother. 2010 Mar;54(3):1358-9.
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