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Chemical Structure : Sotigalimab
CAS No.:
Catalog No.: PC-Ab1065Not For Human Use, Lab Use Only.
Sotigalimab (APX005M) is a humanized monoclonal antibody that binds CD40 with high affinity and activates antigen presenting cells (dendritic cells, monocytes and B cells) leading to stimulation of cancer-specific T-cell responses. This CD40 monoclonal antibody with chemotherapy induces T-cell-dependent tumour regression in mice and improves survival, triggers a multifaceted immune response that brings several components of the immune system together to attack the cancer..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | $358 | In stock | |
| 5 mg | $758 | In stock | |
| 10 mg | $1280 | In stock | |
| 100 mg | Get quote |
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Sotigalimab (APX005M) is a humanized monoclonal antibody that binds CD40 with high affinity and activates antigen presenting cells (dendritic cells, monocytes and B cells) leading to stimulation of cancer-specific T-cell responses. This CD40 monoclonal antibody with chemotherapy induces T-cell-dependent tumour regression in mice and improves survival, triggers a multifaceted immune response that brings several components of the immune system together to attack the cancer.
| M.Wt | ||
| Formula | Human IgG1-Kappa | |
| Appearance | Solid | |
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| Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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