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Soxataltinib

Chemical Structure : Soxataltinib

CAS No.: 2546116-88-3

Soxataltinib

Catalog No.: PC-25020Not For Human Use, Lab Use Only.

Soxataltinib (Example 7) is a potent, selective inhibitor of RET-kinase with IC50 of 0.601 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Soxataltinib (Example 7) is a potent, selective inhibitor of RET-kinase with IC50 of 0.601 nM.

Physicochemical Properties

M.Wt 522.61
Formula C29H30N8O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO

Chemical Name/SMILES

6-(3-hydroxy-3-methylazetidin-1-yl)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile

References

1. Patent CN112209925 A 2021-01-12.

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