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Spiradoline mesylate

Chemical Structure : Spiradoline mesylate

CAS No.: 87173-97-5

Spiradoline mesylate (U 62066)

Catalog No.: PC-61887Not For Human Use, Lab Use Only.

Spiradoline (U 62066) is a potent, highly selective κ-opioid agonist that has analgesic diuretic and antitussive effects..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Spiradoline (U 62066) is a potent, highly selective κ-opioid agonist that has analgesic diuretic and antitussive effects.

Pain

Phase 2 Discontinued

Physicochemical Properties

M.Wt 521.494
Formula C23H34Cl2N2O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-8-yl]acetamide mesylate

References

1. Peters GR, et al. J Pharmacol Exp Ther. 1987 Jan;240(1):128-31.

2. Kamei J, et al. Eur J Pharmacol. 1990 Oct 9;187(2):281-6.

3. Kunihara M, et al. Life Sci. 1989;45(13):1191-8.

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