Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Squarunkin A
CAS No.: 2101958-02-3
Catalog No.: PC-38544Not For Human Use, Lab Use Only.
Squarunkin A is a small molecule UNC119-cargo interaction inhibitor, selectively inhibits the binding of the N-terminus of Src kinase to UNC119A with IC50 of 10 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $88 | In stock | |
| 10 mg | $138 | In stock | |
| 25 mg | $248 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Squarunkin A is a small molecule UNC119-cargo interaction inhibitor, selectively inhibits the binding of the N-terminus of Src kinase to UNC119A with IC50 of 10 nM.
Squarunkin binds to UNC119 proteins in cell lysate and interferes with the activation of Src kinase.
Small-molecule inhibition of the UNC119-cargo interaction might provide new opportunities for modulating the activity of Src kinases.
| M.Wt | 523.557 | |
| Formula | C25H32F3N5O4 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Ethyl 4-((3,4-dioxo-2-((2-(4-(3-(trifluoromethyl)-phenyl)-piperazin-1-yl)-ethyl)-amino)-cyclobut-1-en-1-yl)-amino)-piperidine-1-carboxylate |
|
1. Tom Mejuch, et al. Angew Chem Int Ed Engl. 2017 May 22;56(22):6181-6186.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
